Cryopreservation is a useful tool for embryo transfer, however, it does induce mitochondrial damages. Since the proper function and quality of the mitochondria are required for embryonic development, frozen-thawed embryos need to recover from the cryopreservation-induced damages during subsequent embryo development. Resveratrol induces mitochondrial biogenesis and autophagy through activation of SIRT1. This review introduces studies addressing the hypothesis that resveratrol may help the recuperation of embryos from mitochondrial damages after vitrification or slow freezing.