Abstract
Vol.37 No.2
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The current status and future tasks of preimplantation genetic test for aneuploidy —the utility and effect in assisted reproductive technology—
JMOR, 37(2) 65-72, 2020
The use of the preimplantation genetic test for aneuploidy (PGT-A) to further the goal of improving the pregnancy rate and/or live birth rate has recently become widespread in assisted reproductive technology. The improving accuracy of the PGT-A is due to advances in biopsy techniques from the embryo stage and the development of molecular biological methods. Using the PGT-A has contributed to improvements in pregnancy and live birth rates, and reductions in the treatment frequency of patients of an advanced maternal age, unexplained repeated pregnancy loss and repeated implantation failure. However, the PGT-A’s utility for the management of patients with diminished ovarian reserve or a mosaic embryo remains a matter of debate. In order for the PGT-A to be used more effectively for improving clinical outcomes, further studies are necessary to gain patients’ and healthcare professionals’ recognition of the PGT-A.
