Japanese society of Ova Research

Abstract

Vol.36 No.2

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Human embryonic stem cells in regenerative medicine
JMOR, 36(2) 91-97, 2019
Department of Reproductive Medicine, Center for Regenerative Medicine, National Center for Child Health and Development (NCCHD), Okura 2-10-1, Setagaya-ku, Tokyo 157-8535, Japan

The aim of regenerative medicine is to restore normal function of damaged tissues, and the application of stem cell technology to drug discovery is also expected. Advancement of regenerative medicine is expected not only in the development of clinical application for intractable diseases, but also in generating biomedical industry. In Japan, the systematic frame which promotes the practical application of regeneration medicine has been arranged to support safe and effective regenerative medicine. The establishment of human embryonic stem (hES) cells was reported in 1998, and a clinical trial (First in Human Trial) using hES cells was conducted in the United States for patients with spinal cord injury in 2010. It is expected to become an epoch-making therapy which can expect the effect for the incurable disease. In this paper, the outline of the development of regenerative medicine is outlined and the perspective in stem cell-based regenerative therapy are described.

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