Abstract
Vol.17 No.1
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Identification of Sodium Alginate-induced Reddish Purple-stained Cells (ARPC) in Mice
JMOR, 17(1) 64-67, 2000
DOI: 10.1274/jmor.17.64
DOI: 10.1274/jmor.17.64
Cell surface marker analyses revealed that sodium alginate-induced reddish purple-stained cells (ARPC) expressed high levels of CD45 (common leukocyte antigen), F4/80, MHC class II antigen and c-kit but little Gr-1 and FceR. This expression pattern is the same as those of resident peritoneal macrophages and thioglycollate-induced macrophages (TG-macrophages), indicating that ARPC are macrophages. Mac-1 and Mac-2 expression patterns of ARPC were similar to TG-macrophages, but F4/80 expression was higher than that of TG-macrophages. In addition, the average size of ARPC is about 1.3 times as large as that of TG-macrophages. These results indicate that ARPC may be a distinct macrophage subset.
