Japanese society of Ova Research

Abstract

Vol.25 No.3

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Mini Review
Reproductive Technologies and Related Studies in the Cynomolgus Monkey
JMOR, 25(3) 133-142, 2008
DOI: 10.1274/jmor.25.133
1Tsukuba Primate Research Center, National Institute of Biomedical Innovation, Tsukuba, Ibaraki 305-0843, Japan
2Bioresource Center, RIKEN, Tsukuba, Ibaraki 305-0074, Japan
3Graduate School of Life and Environmental Science, University of Tsukuba, Tsukuba, Ibaraki 305-8572, Japan
4The Center for Disease Biology and Integrative Medicine, Faculty of Medicine, University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan

In mice, basic reproductive technologies, such as oocyte/sperm collection, embryo production, micromanipulation, and embryo transfer, have been established. With these technologies, production of transgenic mice has become routine. The cynomolgus monkey, which is one of the laboratory animals closest to human beings, has been used to obtain vaccine approval and for medical research. Therefore, production of transgenic animals in the monkey is a very significant subject. We describe herein the current state of related studies in addition to current findings regarding reproductive technologies.

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