Abstract
Vol.43 No.2
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Laboratory management for stable culture outcomes and safe handling in ART laboratories
JMOR, 43(2) 77-96, 2026
In assisted reproductive technology (ART), gametes and embryos are handled outside the human body; therefore, the quality of laboratory management influences not only culture performance but also clinical outcomes, including pregnancy and live birth rates. ART laboratories are required to establish and maintain conditions that mimic the in vivo environment as closely and as consistently as possible. This includes controlling temperature, humidity, gas conditions, pH, osmolality, light exposure, volatile organic compounds (VOCs), microbial contamination, and equipment-related failures. In addition, risk management must be implemented in an integrated manner through standardized procedures covering the working environment, culture environment, equipment maintenance, specimen identification, record management, staff training, routine inspection, calibration, cleaning, lot control, and emergency responses to disasters or power outages. This article reviews the fundamental concepts and practical points of ART laboratory management from the perspectives of working environment, culture environment, equipment management, and risk management.
