Mechanism and procedure of Piezo-ICSI - Journal of Mammalian Ova Research (JMOR)

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Vol.42 No.2

Mechanism and procedure of Piezo-ICSI

JMOR, 42(2) 55-63, 2025

¹Kameda IVF Clinic Makuhari, 1-3 Nakase, Mihama-ku, Chiba 261-8501, Japan, ²Kameda Medical Center, 929 Higashi-cho, Kamogawa, Chiba 296-8602, Japan, ³Institute of SCIENCE TOKYO, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan, ⁴KAMEDA INSTITUTE OF NURSING AND ADVANCED PRACTICE, 1343-4 Higashi-cho, Kamogawa, Chiba 296-0041, Japan

Intracytoplasmic sperm injection (ICSI) is an essential technique in infertility treatment. Piezo-ICSI uses a piezo element to semiautomatically perform sperm immobilization, zona opening, and membrane breakage. If Piezo-ICSI is not performed correctly, it only ruptures the oocyte. The degeneration rate, normal fertilization rate, and blastocyst development rate of Piezo-ICSI performed by our four embryologists in 2024 were 2.0% (74/3,716), 84.7% (3,149/3,716), and 69.9% (2,170/3,104), respectively. This article introduces the mechanism and procedure of Piezo-ICSI.

Keywords: Piezo-ICSI Vienna consensus Degeneration rate Normal fertilization rate Blastocyst development rate

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