Abstract
Vol.41 No.2
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Original
Impact of Injection Speed of Embryo Transfer on Pregnancy Rate
JMOR, 41(2) 87-94, 2024
Purpose: To evaluate the association between the injection speed of embryo transfer (ET) and pregnancy rate after frozen–thawed single ET. Methods: This study retrospectively analyzed 2,852 frozen–thawed single ET of 1,243 infertile couples performed at the Ikebukuro Ezaki Ladies Clinic between January 2012 and September 2016. Results: We calculated the representative Group I (fast ET) and Group II (slow ET) speeds. The mean speed of injection of Group I was 7.2 cm/s (range: 5.0–9.2 cm/s, n=15), and that of Group II was 1.1 cm/s (range: 0.3–2.7 cm/s, n=20). An equal distribution (P = 0.07) of the main transfer cycle characteristics was observed for Groups I and II (fast and slow ET). In patients ≥40 years of age, who underwent cleavage-stage ETs, the pregnancy rate was higher in Group I: 17.0% versus 7.4%, P < 0.01. In patients <40 years of age, who underwent blastocyst transfers, the pregnancy rate was lower in Group I: 48.1% versus 56.7%, P < 0.01. Conclusion: Our results demonstrate that the injection speed of ET is related to the pregnancy rate, and that a rapid injection speed was effective for cleavage-stage ETs in patients ≥40 years of age.
