Japanese society of Ova Research

Abstract

Vol.41 No.2

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Evaluation of non-wash semen parameter for intrauterine insemination via Computer-Assisted Semen Analysis
JMOR, 41(2) 75-78, 2024
Masato Saito* Hirofumi Haraguchi Shiryu Miyazaki Hayato Sakai Yoshiko Baba Miku Yotsu Terumi Kawakami Wakako Miura Nanako Shinozaki Megumi Sato Ikumi Nakajima Norio Masuya Kazunori Matsumoto Tomoki Tanaka Leona Matsumoto 
Matsumoto Ladies IVF Clinic, ROKUMARUGATE IKEBUKURO Bld., 1-13-6 Higashiikebukuro, Toshima-ku, Tokyo 170-0013, Japan

This study aimed to assess factors associated with pregnancy in intrauterine insemination (IUI) by analyzing non-wash semen parameters with computer-assisted semen analysis (CASA). This retrospective study included 115 matched pairs from 1,685 IUI cycles performed between January 2021 and May 2022. The associations of semen motility rate, average path velocity (VAP), and straight-line velocity (VSL) with the pregnancy were investigated. The pregnant group had significantly higher motility rates (52.6% vs. 45.1%, P = 0.011), VAP (28.3 μm/s vs. 27.3 μm/s, P = 0.038), and VSL (16.3 μm/s vs. 14.8 μm/s, P = 0.012) compared to the nonpregnant group. The Receiver Operating Characteristic (ROC) curve indicated that 48.8% motility, 30.2 μm/s VAP, and 14.4 μm/s VSL were the optimal thresholds. In conclusion, the motility rate, VAP, and VSL were associated with pregnancy after IUI.

Keywords: CASA  IUI  Motility  VSL  VAP 
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